Since science and technology are intertwined with literature, a great number of writers have created different depictions under the label of Science Fiction which mostly shows various aspects of future human, life, culture, and society. Science Fiction will be exemplified through a number of notable Science Fiction stories in this paper; afterwards, it will outline various notable critics’ notions about future forms of humans including cyborg, transhuman and posthuman, to examine two goals of immortality and superiority in Science Fiction. In sum, this is a literary review paper which presents an overview on Science Fiction and offers a broad discussion on the transformations including cyborg, transhuman and posthuman to distinguish these concepts from each other: transhuman as a transcended human, posthuman as an obsolete human, and cyborg as a machine man.