This linguistic review analyzes the ideas embodied in the scholarly discourse of N. F. Alefirenko, Honored Scientist of the Russian Federation and a leading expert in phraseology, linguacultural studies, linguacognitive semiotics, and discourse linguistics, in the context of current trends in the multiparadigmatic nature of modern linguistics. It is noted that the scholar's scientific conception formulates a unique, innovative, and conceptually sound perspective on the nature of linguo-semiosis in units of indirectly derived nomination as vivid representatives of the value-semantic space of language. The vectors of N. F. Alefirenko's scientific ideas allow for a detailed understanding of problematic areas of linguistics related to identifying the mechanisms of interaction between language, culture, and thought. The scholar's fundamental works form a theoretical platform that facilitates the development of a number of related linguistic disciplines, primarily cultural linguistics, discursive linguistics, and cognitive semiotics. They also explore productive interactions and shed light on the ethnocultural factors of communication, including the encoding and decoding of ethnocultural worldviews, and the formation and development of linguistic personalities. The purpose of this study is to substantiate the significance of N.F. Alefirenko's theory of the value-semantic space of language in the development of a modern anthropocentric approach to language as a tool of cultural creativity and an applicator of the mental space of language, demonstrating the continuity and dynamism of Professor N.F. Alefirenko's scientific school. The relevance of this work is determined by the importance of understanding the scholar's scientific contribution to the interdisciplinary space of modern scientific knowledge through extralinguistic and linguistic interaction. The review states that the scholar made a significant contribution to the formation of the modern multiparadigmatic approach in linguistics, which studies the "language-speech-text-discourse" system, both taking into account classical theories of the 19th and 20th centuries and appealing to the current experience of modern linguosemantic theory, enriched by the methodological approach of related linguistic sciences. Particular attention is given to the works of N.F. Alefirenko's work in phraseology and cultural linguistics, which significantly enriched the modern theory of indirectly derived nomination, his research on the figurative component of linguistic meaning and the connection between linguistic imagery and the culturally marked meaning of a linguistic unit, as well as his works substantiating the lingua-synergistic nature of linguistic semiosis and the cognitive-discursive approaches of cultural linguistics to language analysis. The conclusion discusses the scholar's role in creating a scientific school and training a whole galaxy of students who develop the fundamental scientific principles of the theory of Honored Scientist of the Russian Federation N. F. Alefirenko.